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  Combination Therapy for Alcohol Dependence

Posted: May 08, 2006 16:27

From: JAMA Vol. 295 No. 17, May 3, 2006



Dr Byrne has suggested the following is an important research study. He will consider doing a more formal summary of it in future to ascertain its relevance to regular medical practice and alcohol dependent citizens seeking treatment. We still need to accept that the more effective options we have, the more subjects we can help.

"The efficacies of medication and behavioral therapies, alone or in combination, for treating alcohol dependence were assessed in the multicenter randomized Combined Pharmacotherapies and Behavioral Interventions (COMBINE) study, in which study participants were randomly assigned to 1 of 9 treatment groups. Anton and colleagues report that patients in all groups had an increased number of days of abstinence. However, patients receiving naltrexone, CBI, or both along with medical management had more days of abstinence and fewer heavy drinking days than patients in other treatment groups."


Link to abstract (full text is available for JAMA subscribers only).
 

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